Gijsbertus T J van der Horst Selected Research

Deoxyribodipyrimidine Photo-Lyase

10/2015	Human papillomavirus mediated inhibition of DNA damage sensing and repair drives skin carcinogenesis.
1/2015	Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA.
11/2006	Differential role of basal keratinocytes in UV-induced immunosuppression and skin cancer.
1/2005	Powerful skin cancer protection by a CPD-photolyase transgene.

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Gijsbertus T J van der Horst Research Topics

Disease

11	Neoplasms (Cancer) 01/2020 - 12/2002
5	Xeroderma Pigmentosum (Kaposi's Disease) 01/2016 - 07/2003
5	Cockayne Syndrome (Syndrome, Cockayne) 01/2016 - 12/2002
3	Carcinogenesis 01/2017 - 01/2005
3	Trichothiodystrophy Syndromes 08/2012 - 05/2002
2	Progeria (Hutchinson Gilford Syndrome) 12/2012 - 08/2006
2	Hypoglycemia (Reactive Hypoglycemia) 01/2007 - 12/2006
1	Ototoxicity 01/2016
1	Hearing Loss (Hearing Impairment) 01/2016
1	Deafness (Deaf Mutism) 01/2016
1	Sensorineural Hearing Loss 01/2016
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/2015
1	Breast Neoplasms (Breast Cancer) 07/2015
1	Disorders of Excessive Somnolence (Hypersomnia) 01/2015
1	Chronic Kidney Failure (Chronic Renal Failure) 01/2015
1	Skin Diseases (Skin Disease) 01/2015
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 03/2014
1	Idiopathic Pulmonary Fibrosis 03/2014
1	Lung Diseases (Lung Disease) 03/2014
1	Fibrosis (Cirrhosis) 03/2014
1	Body Weight Changes 02/2014
1	Body Weight (Weight, Body) 02/2014
1	Osteosarcoma (Osteogenic Sarcoma) 02/2014
1	Insulin Resistance 05/2013
1	Hyperinsulinism (Hyperinsulinemia) 05/2013
1	Obesity 05/2013
1	Leukemia 01/2013
1	Hypertension (High Blood Pressure) 01/2010
1	Starvation 08/2008
1	Cerebellar Ataxia (Dysmetria) 12/2006
1	Hypersensitivity (Allergy) 12/2006
1	Dwarfism 12/2006
1	Premature Aging 12/2006
1	Skin Neoplasms (Skin Cancer) 01/2005
1	Weight Loss (Weight Reduction) 09/2004
1	Contact Dermatitis (Eczema, Contact) 10/2003
1	Male Infertility (Male Sterility) 02/2002

Drug/Important Bio-Agent (IBA)

4	Deoxyribodipyrimidine Photo-LyaseIBA 10/2015 - 01/2005
4	Proteins (Proteins, Gene)FDA Link 10/2015 - 07/2003
2	MelatoninIBA 07/2015 - 01/2015
2	AntioxidantsIBA 03/2014 - 01/2007
2	EnzymesIBA 01/2013 - 01/2005
2	8-hydroxyguanineIBA 12/2012 - 12/2002
2	A-Form DNA (A-DNA)IBA 02/2007 - 05/2002
2	Growth Hormone (Somatotropin)IBA 01/2007 - 12/2006
2	Insulin-Like PeptidesIBA 01/2007 - 12/2006
2	NucleotidesIBA 12/2006 - 08/2006
1	XenobioticsIBA 01/2017
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2017
1	Cisplatin (Platino)FDA LinkGeneric 01/2016
1	DNA AdductsIBA 01/2016
1	DNA (Deoxyribonucleic Acid)IBA 01/2016
1	Pyrimidine DimersIBA 10/2015
1	Oncogene Proteins (Oncogene Protein)IBA 10/2015
1	Vitamin D FDA LinkGeneric 07/2015
1	Tamoxifen FDA LinkGeneric 07/2015
1	Messenger RNA (mRNA)IBA 01/2015
1	Bleomycin (Blenoxane)FDA LinkGeneric 03/2014
1	Glutathione (Reduced Glutathione)IBA 03/2014
1	Irinotecan (Camptosar)FDA LinkGeneric 02/2014
1	valspodar (PSC 833)IBA 02/2014
1	LipidsIBA 05/2013
1	Histones (Histone)IBA 01/2013
1	Oxidants (Oxidizing Agents)IBA 12/2012
1	potassium bromateIBA 12/2012
1	Transcription Factor TFIIHIBA 08/2012
1	SaltsIBA 01/2010
1	AldosteroneIBA 01/2010
1	Oxidoreductases (Dehydrogenase)IBA 01/2010
1	MineralocorticoidsIBA 01/2010
1	Biological ProductsIBA 08/2008
1	Oxygen (Dioxygen)IBA 03/2008
1	CarcinogensIBA 01/2007
1	Liver GlycogenIBA 01/2007
1	Blood Glucose (Blood Sugar)IBA 12/2006
1	Diethylhexyl Phthalate (DEHP)IBA 09/2004
1	Picryl Chloride (Trinitrochlorobenzene)IBA 10/2003
1	Mitochondrial DNA (mtDNA)IBA 12/2002
1	UbiquitinIBA 02/2002

Therapy/Procedure

1	Therapeutics 01/2020
1	Chronotherapy 01/2020
1	Drug Therapy (Chemotherapy) 01/2016
1	Renal Dialysis (Hemodialysis) 01/2015